A video showing how bacteria mutate to become super bacteria has gone viral. The experiment done by Roy Kishony and his team involved a large petri dish surface, e.coli bacteria, and antibiotics.
What they did was to put weaker antibiotics towards the edges of the surface, the most powerful antibiotics in the center, and a weak e.coli bacteria which began evolving, or mutating its way through the antibiotic areas. It slowly but surely defeated every antibiotic known to man.
Scientists observed how bacteria mutate, and this could help them design better antibiotics and dose them in just the right amounts.
As more and more drug resistant infections happen in hospitals across the world, this experiment has proven to be extremely useful in understanding the mechanism of bacteria mutations.
Scientists came up with an easier way to demonstrate how bacteria evolve as they develop new strains which can take on the most powerful drugs.
The experiments allow the public to watch how bacteria becomes more and more dangerous by learning to adapt, in order to thrive inside its host.
To achieve this movie-like stunt, where bacteria had the main role, the team used a two-by-four feet petri dish which was then filled with 14 liters of agar. Agar is a jelly substance which is used in laboratories to feed organisms and help them grow.
The petri dish was divided into different areas, which made it easy to observe how bacteria become stronger as the antibiotics become more powerful too.
The trick was that the antibiotic was not enough to kill the bacteria at first, but enough to allow it to mutate. Towards the center, the amount of antibiotic was increased by 10 times.
A camera on the ceiling took two weeks of footage which turned into an intriguing time-lapse.
The result was a vibrant story of death and survival, while evolution took its course. For the first time in history, this type of bacterial development was visible to the naked eye.
Scientists gained valuable insights on how bacteria physically move across a space they slowly conquer, as they mutate to resist in different mediums.
The study was published in the journal Science.
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Image Source – Pixabay